Peer pressure often evokes unexpected behavior, and protein partners might do the same. The Methyl-CpG binding protein 2 (MeCP2) has long been considered a transcriptional repressor, given its ...

During development, many crucial genes help organisms form properly. One of those genes is myogenic determination gene number 1 (MyoD), which can exert a powerful influence as a “genome organizer." It ...

Lambda's 'genetic switch' responds in a dramatic all-or-none fashion to an environmental signal, activating transcription of certain genes as it turns off others. The switch illustrates principal ...

Figure 1: Using an in cellulo mammalian cell-culture system for the physical simulation of natural transcriptional circuits. Figure 2: Proof-by-synthesis of daytime and night-time transcriptional ...