Autoimmune disease occurs from the body’s immune system attacking its healthy cells. Unfortunately, the mechanism that would normally prevent autoimmunity is not present in some individuals. T cells ...

More than two decades ago, a research team discovered a type of T cell in humans that suppresses the immune system; they later found that these so-called regulatory T cells, when defective, are an ...

Autoimmune diseases arise when the immune system mistakenly targets and damages the body’s cells and tissues as though they were foreign invaders. This widespread category of illnesses, such as ...

Northwestern Medicine scientists in the laboratory of Stephen Miller, Ph.D., professor emeritus of Microbiology–Immunology, have identified the cellular and molecular mechanisms required for the ...

July 2, 2010 — Alopecia areata (AA), a hair-loss disease often considered similar to psoriasis because of the inflammation and T-cell involvement, shares many genetic associations with a broad ...

Scientists have developed a new screening tool to uncover how genetic changes affect gene activity and can lead to diseases such as cancer, autoimmunity, neurodegeneration and cardiovascular disease.

The immune system’s capacity to distinguish self from non-self is in large part mediated by immunoglobulins, with IgG playing a pivotal role in both protective and pathological responses.

The first keynote presentation of this week's Keystone meeting on autoimmunity and transplantation tolerance ended in a rather surprising way -- the speaker was actually heckled during the question ...

Multiple sclerosis (MS) is a chronic autoimmune disease caused by the interaction between environmental factors, such as high dietary salt intake, and genetic risk factors. When regulatory T cells, ...

"Medical Journeys" is a set of clinical resources reviewed by physicians, meant for the medical team as well as the patients they serve. Each episode of this 12-part journey through a disease state ...