Whole-genome sequences provide a rich source of information about human evolution. Here we describe an effort to estimate key evolutionary parameters based on the whole-genome sequences of six ...

Empirical Bayes is a versatile approach to “learn from a lot” in two ways: first, from a large number of variables and, second, from a potentially large amount of prior information, for example, ...

Whether in everyday life or in the lab, we often want to make inferences about hypotheses. Whether I’m deciding it’s safe to run a yellow light, when I need to leave home in order to make it to my ...