Odontoblasts, the cells that form a tooth's dentin, have a newly discovered function: Sensing cold, which can trigger pain in teeth; but scientists have also found a way to block the pathway to ...

An ion channel called TRPC5 acts as a molecular cold sensor in teeth and could serve as a new drug target for treating toothaches. For people with tooth decay, drinking a cold beverage can be agony.

There’s a special type of pain when something that is just too cold hits your teeth. This pain is so visceral, medical textbooks written throughout human history have recounted tales of a “tooth worm, ...

Tooth pain is one of those symptoms that’s hard to ignore because it can interfere with eating, sleeping, and even thinking clearly. Sometimes it shows up as sharp sensitivity, other times as a dull ...

Researchers figured out how a jolt of discomfort gets from the damaged outside of your tooth to the nerves inside it. By Veronique Greenwood There’s nothing quite like the peculiar, bone-jarring ...

Researchers report in Science Advances that they have uncovered a new function for odontoblasts, the cells that form dentin, the shell beneath the tooth's enamel that encases the soft dental pulp ...

For people with tooth decay, drinking a cold beverage can be agony. "It's a unique kind of pain," says David Clapham, vice president and chief scientific officer of the Howard Hughes Medical Institute ...