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Distinct tau chemical signatures redefine diagnosis across neurodegenerative diseases
Tau protein aggregation is a shared feature in over 20 neurodegenerative diseases (collectively referred to as "tauopathies") ...
Explore the complexities of tauopathies and how new research could change their diagnosis and treatment approaches.
Researchers headed by a team at the Centre for Genomic Regulation, Barcelona Institute of Science and Technology and at the Wellcome Sanger Institute have developed an AI tool that they say has made a ...
Proteins form the building blocks of life, but when they form unusual clumps inside the brain, they raise an alarm that ...
A new large-scale study has mapped the first molecular events that drive the formation of harmful amyloid protein aggregates found in Alzheimer's disease, pointing toward a new potential therapeutic ...
Micro- and nanoplastics are increasingly detected in human tissues, including the brain, and experimental evidence suggests ...
Back when James Parkinson first described the disorder now known as Parkinson’s disease, he noticed that severe constipation can be a prelude to the signature tremors. In the 208 years since then, ...
In patients with Huntington’s disease, proteins misfold and clump together. Researchers imagine the treatment could potentially someday be administered as a once-weekly injection to delay disease ...
Researchers have developed a 'self-driving' microscope that can predict the onset of misfolded protein aggregation - a hallmark of neurodegenerative disease - as well as analyze the biomechanical ...
Scientists can now zoom in on protein segments in living cells, tracking changes linked to early disease and aiding drug screening for aggregation disorders. The research team engineered a fluorescent ...
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