Pyroptosis is a proinflammatory type of cell death that is associated with gasdermin-mediated membrane hole formation, as well as cell enlargement and lysis. Pyroptosis plays an important role in both ...
About 50% of the adult population throughout the world over the age of 70 years has chronic kidney disease (CKD) and renal fibrosis. Both CKD and renal fibrosis begin as pyroptosis, during which a ...
A sum of 921 samples were collected from three independent data sets. We obtained pyroptosis-related genes from both the Molecular Signatures Database and relevant literature sources and used four ...
The field of cancer biology has recently recognized the significance of immunogenic cell death (ICD), a process by which dying cells emit alarm ...
A novel pathological finding, "BABA", for a prognostic factor in oral tongue carcinoma. This is an ASCO Meeting Abstract from the ASCO Breakthrough: A Global Summit for Oncology Innovators. This ...
This schematic shows the cell death pathway called pyroptosis, Greek for going down in flames. When activated by a toxin or an infection, the enzyme caspase-1 initiates several reactions inside of the ...
Chengdu Baiyu Pharmaceutical Co. Ltd. has synthesized NLRP3 inflammasome inhibitors acting as pyroptosis inhibitors reported to be useful for the treatment of cancer, autoimmune, cardiovascular, ...
Recently, a team led by Academician Hongjie Zhang, Researcher Shuyan Song, Associate Researcher Pengpeng Lei, and Dr. Ran An at the Changchun Institute of Applied Chemistry, Chinese Academy of ...
Researchers from Sun Yat-sen University and affiliated organizations published data from a study that aimed to assess the role of the TNF receptor-associated factor 6 (TRAF6), E3 ubiquitin ligase ...
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