The insulin receptor (IR) is a prototypical receptor tyrosine kinase that orchestrates critical cellular processes, including metabolism, cell growth and differentiation. Activation of the IR involves ...
The intricate regulation of receptor tyrosine kinases (RTKs) underpins a vast array of cellular responses that are essential for growth, differentiation and survival. In particular, the interplay ...
In a discovery that could guide the development of next-generation antidepressants and antipsychotic medications, researchers at the Icahn School of Medicine at Mount Sinai have developed new insights ...
Researchers at the NYU Pain Research Center have found a new receptor for nerve growth factor that plays an important role in pain signaling, even though it does not signal on its own, according to a ...
Estrogen plays an important role in keeping bones healthy. Now, researchers investigated how membrane-initiated estrogen receptor alpha (mERα) signaling in specific cell types of female mice affects ...
Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results, researchers are now watching individual molecules collide with cell ...
Scientists at École Polytechnique Fédérale Lausanne (EPFL), and at UNIL-CHUV, University Hospital Lausanne (CHUV) and University of Lausanne (UNIL) have developed a computational method to create ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results