Scientists at St. Jude Children's Research Hospital have characterized a hidden intermediate state at the center of Src kinase function. This hidden state allows the kinase to repeatedly modify its ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No. 32 (August 10, 2021), pp. 1-11 (11 pages) Family with sequence similarity 20C (Fam20C), the major protein ...
As society ages, the number of patients with heart failure is rapidly increasing. The progression of the disease is caused by excessive growth of fibrotic tissue in the heart, known as fibrosis. A ...
Researchers from the Icahn School of Medicine at Mount Sinai have introduced KiNet, an interactive web portal designed to explore kinase-substrate interactions in human cellular systems. These ...
(MEMPHIS, Tenn. – December 18, 2025) Scientists at St. Jude Children’s Research Hospital have characterized a hidden intermediate state at the center of Src kinase function. This hidden state allows ...